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PEPE surges 4% as market sentiment improves, eyes Key resistance breakout

by Bitcoin News Update
April 22, 2026
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Key takeaways

Pepe extends gains on Wednesday, stretching its rally from the 50-day EMA.
Derivatives data show heightened retail activity as risk-on sentiment returns to the market.

Pepe (PEPE) is experiencing a steady rally on Wednesday, trading in the green for the third consecutive day. The frog-themed meme coin is gaining traction as broader market sentiment improves, lifting retail demand for meme coins.

Market sentiment boosts meme coin demand

The broader market’s upside, despite ongoing geopolitical tensions surrounding the US-Iran blockade of the Strait of Hormuz and faltering peace talks, is boosting retail interest in meme coins. 

According to CoinMarketCap, the Fear and Greed Index is at 62 on Wednesday, showing a consistent rise in risk appetite since the US-Iran ceasefire announcement.

On the derivatives side, the PEPE futures Open Interest (OI) stands at $213.25 million, with a 7% increase in the last 24 hours. 

This surge in futures positions indicates growing participation from traders, aligning with the recovery in the spot price—further supporting a bullish outlook for PEPE.

Pepe tests breakout of key resistance level

The PEPE/USD 4-hour chart is bullish and efficient as Pepe’s short-term recovery remains intact, with a three-day rebound from the 50-day Exponential Moving Average (EMA) at $0.00000368.

However, PEPE is still trading below the 100-day and 200-day EMAs, which could cap the ongoing rally.

The Relative Strength Index (RSI) at 60 is edging higher from the midline, indicating mild positive momentum. Meanwhile, the Moving Average Convergence Divergence (MACD) remains above its signal line, keeping the histogram bars positive.

At press time, PEPE is trading at $0.00000393. If the rally should continue, PEPE must break above its descending trendline near $0.00000400, close to the 100-day EMA at $0.00000404. 

PEPE/USD 4H Chart

A breakout above this level could pave the way for a rally toward the 200-day EMA around the $0.00000500 psychological resistance. 

On the downside, the 50-day EMA at $0.00000368 provides immediate dynamic support, with further downside protection at the February 6 low of $0.00000311.

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